Mission District Vacation Packages

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  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
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    With over 300,000 hotels worldwide, it's easy to create a perfect package
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    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Mission District

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Fisherman's Wharf
 The Huntington Hotel
The Jay, Autograph Collection
1 Hotel San Francisco
Beacon Grand, A Union Square Hotel

Where to stay in Mission District

Find the best Mission District areas and neighborhoods for the activities you enjoy most. Learn more about Mission District

Mission District Hotel Deals

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $204 per night from Jun 28 to Jun 29
CA $204
CA $297 total
Jun 28 - Jun 29
includes taxes & fees
9/10 Wonderful! (7,598 reviews)
"The room was spacious and clean. Location is very convenient and close to Fisherman's Wharf. The breakfast was excellent!"

Reviewed on Jun 14, 2026

Hotel Riu Plaza Fisherman's Wharf
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
The price is CA $201 per night from Jul 12 to Jul 13
CA $201
CA $237 total
Jul 12 - Jul 13
includes taxes & fees
9/10 Wonderful! (5,856 reviews)
"Staff was great and very helpful, parking the car to go check in was a pain, stressful and not a lot of room and line was going out to the street. Hotel was nice inside, didn’t realize there was no microwave in the room which was a bummer and we had to call to figure out if there were blackout curtains ..."

Reviewed on Jun 14, 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
The price is CA $248 per night from Jun 28 to Jun 29
CA $248
CA $292 total
Jun 28 - Jun 29
includes taxes & fees
8.6/10 Excellent! (1,368 reviews)
"Inside was fairly clean. The outside could use a power spray cleaning at least every week from the smell of urine. Luggage Staff was extremely helpful. Check-in Staff that helped me could be more friendly to encourage customers to come back. Overall stay was okay to good."

Reviewed on Jun 8, 2026

Hilton San Francisco Union Square
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission District vacation package cost?
Our Mission District packages, which begin at just CA $1,423, are an awesome way to save big. Pick your favorite flights, hotels and rental cars to create a customized escape.
How do I get a cheap travel package to Mission District?
By bundling. Flights, rental cars and hotels — combine whatever you need into a Mission District vacation package to save a pile of cash. Score even more deals when you add extras such as sightseeing tours to your booking. But that's not the only impressive part. You have the freedom to customize your vacation your own way. We offer more than 550 partner airlines and 1,000,000 hotels worldwide, so that everyone has a chance to travel and live out those vacation dreams.
Where should I stay in Mission District?
A visit to Mission District isn't complete until you've seen Pier 39 and Alcatraz Island. Book a room close by for quick access to these popular attractions.
What are the top hotels in Mission District?
If it's your first time staying in Mission District, lock in a room at 1906 Mission or Charming And Cozy Dolores Park Condo By Redawning. Both will make you feel at home and are favorites among lots of travelers.
How far in advance should I book my Mission District vacation?
To bag rock-bottom prices, book ASAP. Airlines usually start selling tickets, along with some of the lowest fares, around 12 months ahead of time. Hotels, car rental and experiences should also be booked early so you can have the pick of the bunch. If you've decided on a last-minute getaway in Mission District, there are always lots of great deals to be had on Expedia. Book your escape today!
What does an Expedia Mission District travel package include?
It all boils down to what sort of getaway you want to have. Mission District vacation deals can include car rentals, hotels and flights. You can mix and match to create the travel package that fits your needs. You can also add on activities and experiences after you've booked to pick up even bigger discounts.
What should I know before booking a Mission District travel package?
Booking all the parts of your escape together is one of the best ways to save. Bundle your car rentals, airfares and hotels into a convenient package. But you're not restricted to hotels. Expedia has all types of properties, including vacation rentals like beachfront villas and serviced residences. You've got loads of choices!
Can I choose my airline with a Mission District Expedia vacation package?
With a vacation package, you're always in charge. Whether you want to fly to Mission District in first class or coach, simply select from the available airline options. Expedia has access to more than 550 airline partners around the world.
If I'm not able to travel, can I cancel my Mission District vacation package?
You sure can, and we're here to help. You may be able to cancel or change your Mission District vacation package for free if you booked in the last 24 hours. But you may incur a fee from your airline, hotel or car rental company if you booked more than 24 hours ago. If your travel plans unexpectedly change, visit our Customer Service Portal for more information.

Stay near popular Mission District attractions

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.